Study on the Role of Osteogenic Gene Variants in Bone Healing Presented at National Orthopedics Congress

“Research by Erhan Yelekçi and Team Draws Significant Interest at the 32nd National Turkish Orthopedics and Traumatology Congress”

From October 31 to November 5, 2023, the 32nd National Turkish Orthopedics and Traumatology Congress was held at the Titanic Belek Convention Center in Antalya, gathering Turkey’s leading orthopedic experts. At this prominent event, the research team led by Erhan Yelekçi presented their study titled “Investigating the Potential Role of Osteogenic Gene Variants in Delayed Bone Healing.” The research meticulously examines the impact of genetic factors on bone fracture healing.

The study focused on the effects of mutations in the BMP4, BMP6, and RUNX2 genes on the healing process of bone fractures. The researchers analyzed DNA samples collected from 30 patients and 30 control subjects, identifying a total of 12 mutations within these genes. Notably, four missense mutations that could adversely affect the bone repair process were highlighted.

The presentation at the congress generated considerable interest among attendees and provided new perspectives on the development of genetic testing and treatment methods, enriching the scientific dialogue in the field of orthopedics and traumatology.

The findings of the research team shed light on a better understanding of the genetic factors involved in the bone healing process, guiding future research in this area. This successful presentation was also supported by a patent application submitted to the Turkish Patent and Trademark Office, enhancing the scientific and commercial potential of the study.

The contributions by Erhan Yelekçi and his team are set to reshape approaches to solving serious bone health issues such as osteoporosis and will provide new directions for research and practice in this field.